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Apply Nightly Defense skincare to the face in a very thin layer (only use a small pea-sized amount for the entire face).Incorporate a gentle face cleanser and moisturizer into your skincare routine.Let your doctor or nurse practitioner know if you have ever used tretinoin in the past and whether you experienced any side effects.To minimize the chances of experience these effects, there are a few things you can try: Topical tretinoin can cause dryness, scaling, and redness of the skin-especially in the first 1–2 weeks. Is Roman skincare appropriate for use while pregnant or breastfeeding? And azelaic acid fights inflammation and reduces the growth of bacteria that contribute to acne. Tretinoin is a retinoid medication that increases the turnover of skin cells, opening pores and releasing bacteria and other irritants that may be trapped inside. That’s why, if you are prescribed Nightly Defense for acne, your formulation will include two anti-acne powerhouses: tretinoin and azelaic acid. Research shows that a combination of treatments-rather than any single treatment alone-may be more effective at addressing the different features of acne. Luckily, there are many different treatments for acne, ranging from over-the-counter topical treatments like benzoyl peroxide, to prescription topical or oral antibiotics, to vitamin A compounds called retinoids. Clearing up the skin and reducing painful inflammation is a goal for many who suffer from acne. Many people have acne, but it can be a frustrating condition to live with. Is Roman’s Nightly Defense skincare an effective treatment for acne? This makes it a good treatment choice for acne without the risk of contributing to antibiotic resistance.įor more information on azelaic acid, see Important Safety Information. Azelaic acid is not an antibiotic, but it does have antibacterial properties and is able to help stop the growth of acne-causing bacteria. Instead of topical antibiotics, one of the possible ingredients in Nightly Defense skincare is azelaic acid. Therefore, antibiotics should only be used when necessary. The over-prescription of antibiotics in society is partly what contributes to antibiotic resistance. Antibiotic-resistant bacteria are bacteria that have evolved in a way that makes them harder to treat with certain antibiotics. However, there is growing public health concern over the emergence of antibiotic-resistant bacteria. Because of this, topical or oral antibiotics are sometimes used for the treatment of acne. Acne, in part, is caused by a bacteria called Cutibacterium acnes (formerly Propionibacterium acnes).